What is Acanthosis Nigricans and how can it be treated

Acanthosis nigricans skin condition that is characterized by the dark discoloration in the folds and creases of the body. The skin that is affected by acanthosis nigricans generally become thick, armpits groin neck are  the most common affected areas of the body, Areas which get affected may also itch and have an odor. Acanthosis nigricans are the signs of some major serious health problems such as prediabetes. 

Most common sites of acanthosis nigricans:-

  • elbow
  • armpit
  • back of the neck
  • lips
  • palms
  • knees
  • sole of the foot
  • under female breast
  • groin

Symptoms:-

The main sign and symptoms of acanthosis nigricans is the noticeable dark thickened and velvety skin most commonly in the folds and creases of the body, these changes in the skin colour usually appears slowly the affected portion may have an bad odor and itching.

Causes:- 

Acanthosis nigricans has been generally associated with

1. Insulin Resistance- most of the people having acanthosis nigricans have also become more resistant to insulin, that is secreted by the pancreas and allowed the body to process sugar. 

2. Medications- certain medications that can trigger acanthosis nigricans are:
  • Injected supplementary insulin
  • Nicotinic acid
  • Systemic glucocorticoid
  • Thyroid medication
  • Protease inhibitors
  • Estrogen
  • Diethylstilbestrol
  • Human Growth hormone
3. Hormonal disorders-  acanthosis nigricans often occurs to the people who have disorders such as Ovarian cysts, adrenal glands problem or underactive thyroids.

Other potential causes include- 
  • Stomach cancer
  • Adrenal gland disorder
  • Pitutary gland disorder
  • Genetics
  • Some autoimmune disorders
  • Low thyroid hormone
  • Growth hormone therapy
Prevention:-
  • Maintaining a proper weight
  • Maintaining proper diet 
  • Keeping proper eye on medicatios are some of the preventive tips to prevent acanthosis nigricans
Treatment:-

1. Loosing weight- if the acanthosis nigricans is caused due to obesity losing weight is the best treatment.

2. Stopping certain medications- if the condition is related to any other type of medications that the patient is using it is recommended to stop that medication or the substance and the supplement that may increase the risk of spread.

3. Surgery- if acanthosis nigricans results due to cancerous tumor surgical removal of the tumor help to clear up the skin's discoloration.

4. If you are concerned about the appearance of your skin or if the lesions become uncomfortable or start to smell bad, here are some of the prescription that the doctor may suggest:-
  • Prescription creams to lighten or soften the affected areas
  • Antibacterial soaps, used gently, as scrubbing could worsen the condition
  • Topical antibiotic
  • Oral acne medications
  • Laser therapy to reduce the skin's thickness
Stabilizing hormones- For people with hormonal disorders, acanthosis nigricans may resolve if they get their condition under control using medications, lifestyle changes, and other treatments.

Managing diabetes- People with type 2 diabetes requires medications, these people also require regular monitoring of blood sugar levels,also the dietary and lifestyle modifications. Also these changes are to maintain insulin levels once it  become stable, acanthosis nigricans symptoms may resolve.


Get the right treatment for your skin with the Skin specialist in Kandivali. Book an appointment call now us 022-28860900/ 9106183902 and online visit https://www.amiskinhairclinic.com/ for more information.


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